Rebel Wilson made headlines for her dramatic weight loss. The celebrated Aussie actress has been flaunting her new trim figure on social media. Well, what got tongues wagging is the stunning and beautiful transformation. Note that Rebel Wilson’s fame was mainly for her “Fat Amy” role in Pitch Perfect Movie. But how is it possible for anyone to lose such a significant amount of weight? Well, you can use prescription drugs such as phentermine. If you are looking for a Rebel Wilson and Phentermine for weight loss type of story, then you need to understand how this drug works.

What is Phentermine?

This is a prescription drug for weight loss. It’s mainly prescribed by doctors for short-term use, preferably up to 12 weeks. This drug also goes by brand names such as Suprenza, Lomaira, and Adipex-P. Additionally, you can find phentermine in other combination medications for weight loss e.g. Qsymia. 

This drug is normally prescribed for obese people. Those with a body mass index of 30 or more. However, in some instances, the doctor can prescribe it to those with body mass index of 27 and have one or more weight-related health condition like type 2 diabetes, high blood cholesterol, and high blood pressure.

Just like other prescription drugs, you need to use phentermine is part of your overall weight-loss plan. This is a schedule IV drug, which means that it has a high potential for abuse. However, its actual potential is very low.

How Does It Work for Weight Loss?

Clinically, phentermine belongs to a class of anorectic drugs. It is, therefore, an effective appetite suppressant. Obese patients who take phentermine end up with a significantly reduced appetite. The drug helps to reduce their overall calorie intake and leads to weight loss with time.

The appetite-reducing effect of phentermine is still not clear. It is, however, thought that it increases the levels of 6Trusted and 7Trusted Sources in the brain. These are neurotransmitters which are chemical messengers and they include dopamine, serotonin, and norepinephrine. 

An increase in the production of these three chemicals normally leads to reduced food cravings. They promote the feeling of satiety and control your appetite. Obese people need to be aware that phentermine is only effective for a short period of time. They, therefore, need to implement an effective diet and workout plan for long-term use. This is because the body will quickly build tolerance to this prescription drug within a few weeks.

Ingredients in Phentermine

The main ingredient that’s in phentermine is Phentermine hydrochloride. This is a compound which is effective in treating obesity. The salt interacts with the central nervous system, leading to a decrease in food cravings. In addition to that, Phentermine hydrochloride also decreases the secretion of gastric acid and increases the metabolic effects.

Phentermine Dosage

Note that there is no specified universal dosage for this drug. Dosage normally varies depending on the concentration and form of phentermine. Doctors normally prescribe the lowest dose approved. In 2016, the FDA approved that obese patients need to take an 8mg formulation, three times per day.

Phentermine for Weight Loss

Benefits of Using Phentermine

The main reason why doctors prescribe this weight loss drug is to spark weight loss. Phentermine is an effective weight loss accelerator. It helps to suppress food cravings in obese and overweight people. As a result, it reduces their daily caloric intake and eventually results in weight loss. Its other benefit is treating eating disorders.

Reducing the Effects of Eating Disorders

If this drug is effectively used in combination with topiramate, it may help to treat certain disorders. People with bulimia nervosa and binge eating disorder can use it to control their food intake. Note that bulimia nervosa is a binge eating behavior but the patient normally engages in self-inducing vomiting. On the other hand, Binge Eating Disorder is highly characterized by consuming large amounts of food in a very quick manner.

Possible Side Effects of Phentermine

Doctors usually prescribe this drug as a short-term solution to patients. However, the FDA has now approved the use of this drug with topiramate for long-term use. This means that you can use this combination for several weeks as you look for alternative measures. Common side effects of phentermine include:

  • Change in sleep patterns
  • Fatigue and dizziness
  • Dry mouth
  • Increased heart palpitations
  • Increased irritability
  • Flushing of the skin and others


Although phentermine is a relatively safe drug, you need to exercise caution before using it. Do not take phentermine if you are a pregnant or nursing mom. In addition to that, avoid using this drug if you suffer from hyperthyroidism, heart disease, and glaucoma.

The Bottom Line

Weight loss heavily relies on the type of diet and workout routine. It’s important to eat well-balanced and low-calorie meals if you want to lose those excess pounds. Besides that, make sure that you are physically active and exercise on a regular basis. However, some people have certain medical conditions which makes it impossible for them to lose weight by observing these things only. They need to take certain drugs in order to shed a significant amount of weight. Phentermine is an effective prescription drug which obese people can use. They can take it in combination with topiramate for long-term use.



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